| Integration Core |
PHD1 controls muscle mTORC1 in a hydroxylation independent manner by stabilizing leucyl tRNA synthetase |
11(1) |
174 |
Gommaar D'Hulst, Ines Soro-Arnaiz, Evi Masschelein, Koen Veys, Gillian Fitzgerald, Benoit Smeuninx, Sunghoon Kim, Louise Deldicque, Bert Blaauw, Peter Carmeliet, Leigh Breen, Peppi Koivunen, Shi-Min Zhao, and Katrien De Bock |
Nature Communications |
20191216 |
| Integration Core |
Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development. |
16 |
31-41 |
Semi Lim, Hye Young Cho, Dae Gyu Kim, Younah Roh, Se-Young Son, Ameeq Ul Mushtaq, Minkyoung Kim, Deepak Bhattarai, Aneesh Sivaraman, Youngjin Lee, Jihye Lee, Won Suk Yang, Hoi Kyoung Kim, Myung Hee Kim, Kyeong Lee, Young Ho Jeon & Sunghoon Kim |
Nature chemical biology |
20191202 |
| Integration Core |
Symmetric Assembly of a Decameric Subcomplex in Human Multi-tRNA Synthetase Complex Via Interactions between Glutathione Transferase-Homology Domains and Aspartyl-tRNA Synthetase. |
431(22) |
4475-4496 |
Ha Yeon Cho, Hyun Joo Lee, Yoon Seo Choi, Dong Kyu Kim, Kyeong Sik Jin, Sunghoon Kim, Beom Sik Kang |
Journal of molecular biology. |
20191108 |
| Integration Core |
ERK-dependent phosphorylation of the linker and substrate-binding domain of HSP70 increases folding activity and cell proliferation |
51(9) |
1-14 |
Semi Lim, Dae Gyu Kim, Sunghoon Kim |
Experimental and molecular medicine |
20190926 |
| Integration Core |
The DRS-AIMP2-EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex. |
6(Pt5) |
958-967 |
Hyunggu Hahn, Sang Ho Park, Hyun-Jung Kim, Sunghoon Kim, and Byung Woo Han |
IUCrJ |
20190901 |
| Integration Core |
Aminoacyl-tRNA synthetases as therapeutic targets |
18(8) |
629-650 |
Nam Hoon Kwon, Paul Fox, Sunghoon Kim |
Nature Reviews Drug Discovery |
20190510 |
| Integration Core |
Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration |
130 |
2088-2093 |
Kook Son, Jae-Sung You, Mee-Sup Yoon, Chong Dai, Jong Hyun Kim, Nidhi Khanna, Aditi Banerjee, Susan A. Martinis, Gyoonhee Han, Jung Min Han, Sunghoon Kim, and Jie Chen |
Journal of Clinical Investigation |
20190416 |
| Integration Core |
Evolution of the multi-tRNA synthetase complex and its role in cancer |
294(14) |
5340-5351 |
Do Young Hyeon, Jong Hyun Kim, Tae Jin Ahn, Yeshin Cho, Daehee Hwang and Sunghoon Kim |
Journal of Biological Chemistry |
20190405 |
| Integration Core |
A threonyl-tRNA synthetase-mediated translation initiation machinery |
10(1) |
1357 |
Seung Jae Jeong, Shinhye Park, Loi T. Nguyen, Jungwon Hwang, Eun-Young Lee, Hoi-Khoanh Giong, Jeong-Soo Lee, Ina Yoon, Ji-Hyun Lee, Jong Hyun Kim, Hoi Kyoung Kim, Doyeun Kim, Won Suk Yang, Seon-Young Kim, Chan Yong Lee, Kweon Yu, Nahum Sonenberg, Myung Hee Kim, Sunghoon Kim |
Nature Communications |
20190322 |
| Integration Core |
HIF1α‐mediated AIMP3 suppression delays stem cell aging via the induction of autophagy |
18(2) |
e12909 |
Chul Kim, Ji‐Min Park, Youngsook Song, Sunghoon Kim, Jisook Moon |
Aging Cell |
20190131 |
| Integration Core |
Structure-activity relationship of leucyladenylate sulfamate analogues as leucyl-tRNA synthetase (LRS)-targeting inhibitors of Mammalian target of rapamycin complex 1 (mTORC1) |
S0968-0896(18) |
32164-3 |
Suyoung Yoon, Sung-Eun Kim, Jong Hyun Kim, Ina Yoon, Phuong-Thao Tran, Jihye Ahn, Changhoon Kim, Woong Sub Byun, Sangkook Lee, Sunghoon Kim, Jiyoun Lee, Jeewoo Lee |
Bioorganic & Medicinal Chemistry |
20190130 |
| Integration Core |
Glycoprotein 96 Polymorphisms are Associated with the Risk of Systemic Lupus Erythematosus: A Case-Control Study |
22(5) |
905-912 |
Jeong Seok Lee, Churl Hyun Im, Sang Jin Lee, Ji Yong Choi, Jung Min Han, Sunghoon Kim, Dong Jo Kim, Taesung Park, Eun Young Lee, Yeong Wook Song |
International Journal of Rheumatic Diseases |
20190127 |
| Integration Core |
Released tryptophanyl-tRNA synthetase stimulates innate immune responses against viral infection |
93(2) |
e01291-18 |
Hyun-Cheol Lee, Eun-Seo Lee, Md Bashir Uddin, Tae-Hwan Kim, Jae-Hoon Kim, Kiramage Chathuranga, W. A. Gayan Chathuranga, Mirim Jin, Sunghoon Kim, Chul-Joong Kim, Jong-Soo Lee |
Journal of Virology |
20190104 |
