|
Amyloid-like oligomerization of AIMP2 contributes to α-synuclein interaction and Lewy-like inclusion |
12(569) |
eaax0091 |
Sangwoo Ham, Seung Pil Yun, Hyojung Kim, Donghoon Kim, Bo Am Seo, Heejeong Kim, Jeong-Yong Shin, Mohamad Aasif Dar, Gum Hwa Lee, Yun Il Lee, Doyeun Kim, Sunghoon Kim, Hee-Seok Kweon, Joo-Ho Shin, Han Seok Ko, Yunjong Lee |
Science translational medicine. |
20201111 |
|
Extracellular vesicles derived from macrophage display glycyl-tRNA synthetase 1 exhibits anti-cancer activity Journal of Extracellular Vesicles |
in press |
|
Peter G. et al. |
Journal of Extracellular Vesicles |
20201107 |
| Target ID |
Structural and functional characterization of Helicobacter pylori DsbG. |
585(24) |
3862-3867 |
Ji Young Yoon, Jieun Kim, Sang Jae Lee, Hyoun Sook Kim, Ha Na Im, Hye-Jin Yoon, Kyoung Hoon Kim, Soon-Jong Kim, Byung Woo Han, Se Won Suh |
FEBS Lett |
20111215 |
| Target ID |
Benzothiazole-containing hydroxamic acids as histone deacetylase inhibitors and antitumor agents. |
21(24) |
7509-7512 |
Dao Thi Kim Oanh, Hoang Van Hai, Sang Ho Park, Hyun-Jung Kim, Byung-Woo Han, Hyung-Sook Kim, Jin-Tae Hong, Sang-Bae Han, Van Thi My Hue, Nguyen-Hai Nam |
Bioorganic & Medicinal Chemistry Letters |
20111215 |
| Integration Core |
Dual role of methionyl-tRNA synthetase in the regulation of translation and tumor suppressor activity of aminoacyl-tRNA synthetase-interacting multifunctional protein-3. |
108(49) |
19635-19640 |
Nam Hoon Kwon, Taehee Kang, Jin Young Lee, Hyo Hyun Kim, Hye Rim Kim, Jeena Hong, Young Sun Oh, Jung Min Han, Min Jeong Ku, Sang Yeol Lee, Sunghoon Kim |
Proceedings of the National Academy of Sciences of the United States of America |
20111206 |
| Target ID |
Survival and differentiation of mammary epithelial cells in mammary gland development require nuclear retention of Id2 due to RANK signaling. |
31(23) |
4775-4788 |
Nam-Shik Kim, Hyoung-Tai Kim, Min-Chul Kwon, Suk-Won Choi, Yoon-Young Kim, Ki-Jun Yoon, Bon-Kyoung Koo, Myung-Phil Kong, Juhee Shin, Yunje Cho, Young-Yun Kong |
Molecular and Cellular Biology |
20111201 |
| Disease Modeling |
Survival and differentiation of mammary epithelial cells in mammary gland development require nuclear retention of Id2 due to RANK signaling. |
31(23) |
4775-4788 |
Nam-Shik Kim, Hyoung-Tai Kim, Min-Chul Kwon, Suk-Won Choi, Yoon-Young Kim, Ki-Jun Yoon, Bon-Kyoung Koo, Myung-Phil Kong, Juhee Shin, Yunje Cho, Young-Yun Kong |
Molecular and Cellular Biology |
20111201 |
| Disease Modeling |
Metformin represses self-renewal of the human breast carcinoma stem cells via inhibition of estrogen receptor-mediated OCT4 expression. |
6(11) |
e28068 |
Ji-Won Jung, Sang-Bum Park, Soo-Jin Lee, Min-Soo Seo, James E. Trosko, Kyung-Sun Kang |
PLoS One |
20111123 |
| Target ID |
Bilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor protein. |
18(12) |
1336-1344 |
Hye-Ra Lee, Won-Chan Choi, Stacy Lee, Jungwon Hwang, Eunha Hwang, Koushik Guchhait, Juergen Haas, Zsolt Toth, Young Ho Jeon, Tae-Kwang Oh, Myung Hee Kim, Jae U Jung |
Nature Structural & Molecular Biology |
20111106 |
| Integration Core |
Entamoeba lysyl-tRNA synthetase contains a cytokine-like domain with chemokine activity towards human endothelial cells. |
5(11) |
e1398 |
Manuel Castro de Moura, Francesc Miro, Jung Min Han, Sunghoon Kim, Antonio Celada, Lluis Ribas de Pouplana |
PLoS Neglected Tropical Disease |
20111105 |
| Target ID |
Crystal structure of Arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 in complex with 8-iso prostaglandin A(1). |
79(11) |
3236-41 |
Byung Woo Han, Thomas E. Malone, Do Jin Kim, Craig A. Bingman, Hyun-Jung Kim, Brian G. Fox, George N. Phillips Jr |
Proteins |
20111101 |
| Drug Screening |
Sphingosylphosphorylcholine attenuated β-amyloid production by reducing BACE1 expression and catalysis in PC12 cells. |
36(11) |
2083-2090 |
Hyoseok Yi, Seong Jin Lee, Jiyeong Lee, Chang-Seon Myung, Woo-Kyu Park, Hee-Jong Lim, Ge Hyeong Lee, Jae Yang Kong, Heeyeong Cho |
Neurochem Res |
20111101 |
| Drug Design |
One target, different effects: a comparison of distinct therapeutic antibodies against the same targets. |
43(10) |
539-549 |
Hyunbo Shim |
Experimental and Molecular Medicine |
20111031 |
| Target ID |
Crystal structure of Mycobacterium tuberculosis Rv3168: a putative aminoglycoside antibiotics resistance enzyme. |
79(10) |
2983-2987 |
Sangwoo Kim, Chi My Thi Nguyen, Eun-Jung Kim, Kyung-Jin Kim |
Proteins |
20111001 |
| Target ID |
Overexpression, crystallization and preliminary X-ray crystallographic analysis of the C-terminal cytosolic domain of mouse anoctamin 1. |
67(Pt 10) |
1250-1252 |
Sang Ho Park, Ho Kyung Chung, Do Jin Kim, Mi Ra Han, Mi Seul Park, Uhtaek Oh, Hyun-Jung Kim, Byung Woo Han |
Acta Crystallogr Sect F Struct Biol Cryst Commun |
20111001 |
| Drug Screening |
Programming magnetic anisotropy in polymeric microactuators. |
10(10) |
747-52 |
Jiyun Kim, Su Eun Chung, Sung-Eun Choi, Howon Lee, Junhoi Kim, Sunghoon Kwon |
Nature Materials |
20111001 |
| Disease Modeling |
Targeted disruption of Mcm10 causes defective embryonic cell proliferation and early embryo lethality. |
1813(10) |
1777-1783 |
Han Jeong Lim, Yoon Jeon, Chang Hwan Jeon, Jong Hyun Kim, Ho Lee |
Biochimica et Biophysica Acta |
20111001 |
| Integration Core |
Aminoacyl-tRNA synthetases and tumorigenesis: more than housekeeping. |
11(10) |
708-718 |
Sunghoon Kim, Sungyong You, Daehee Hwang |
Nature Reviews Cancer |
20110928 |
| Integration Core |
Enhancement of toll-like receptor 2-mediated immune responses by AIMP1, a novel cytokine, in mouse dendritic cells. |
134(1) |
73–81 |
Eugene Kim, Hye-Jin Hong, Daeho Cho, Jung Min Han, Sunghoon Kim, Tae Sung Kim |
Immunology |
20110901 |
| Drug Screening |
In situ fabrication and actuation of polymer magnetic microstructures. |
20(1) |
785-787 |
Su Eun Chung, Jiyun Kim, Sung-Eun Choi, Lily Nari Kim, Sunghoon Kwon |
JMEMS Letters |
20110801 |
| Target ID |
Crystal structure of the Mre11-Rad50-ATPγS complex: understanding the interplay between Mre11 and Rad50. |
25(10) |
1091-1104 |
Hye Seong Lim, Jin Seok Kim, Young Bong Park, Gwang Hyeon Gwon, Yunje Cho |
Genes & Development |
20110515 |
| Integration Core |
Importin beta plays an essential role in the regulation of the LysRS-Ap(4)A pathway in immunologically activated mast cells. |
31(10) |
2111-2121 |
Irit Carmi-Levy, Alex Motzik, Yifat Ofir-Birin, Zohar Yagil, Christopher Maolin Yang, David Michael Kemeny, Jung Min Han, Sunghoon Kim, Gillian Kay, Hovav Nechushtan, Ryo Suzuki, Juan Rivera, Ehud Razin |
Molecular and Cellular Biology |
20110501 |
| Target ID |
Solution structure of the Zbeta domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B- and Z-DNAs. |
108(17) |
6921-6926 |
Kyungmin Kim, Bulat I. Khayrutdinov, Chung-Kyung Lee, Hae-Kap Cheong, Sung Wook Kang, Hyejin Park, Sangho Lee, Yang-Gyun Kim, JunGoo Jee, Alexander Rich, Kyeong Kyu Kim, Young Ho Jeon |
Proceedings of the National Academy of Sciences of the United States of America |
20110426 |
| Integration Core |
Cancer-associated splicing variant of tumor suppressor AIMP2/p38: pathological implication in tumorigenesis. |
7(3) |
e1001351 |
Jin Woo Choi, Dae Gyu Kim, Al-Eum Lee, Hye Rim Kim, Jin Young Lee, Nam Hoon Kwon, Young Kee Shin, Soon-Kyung Hwang, Seung-Hee Chang, Myung-Haing Cho, Yoon-La Choi, Jhingook Kim, Seung Hyun Oh, Bora Kim, Soo-Youl Kim, Hyo-Sung Jeon, Jae Yong Park, Hyunseok Peter Kang, Bum Joon Park, Jung Min Han, Sunghoon Kim |
PLoS Genetics |
20110301 |
| Integration Core |
GARNET-gene set analysis with exploration of annotation relations. |
12(Suppl 1) |
S25 |
Kyoohyoung Rho, Bumjin Kim, Youngjun Jang, Sanghyun Lee, Taejeong Bae, Jihae Seo, Chaehwa Seo, Jihyun Lee, Hyunjung Kang, Ungsik Yu, Sunghoon Kim, Sanghyuk Lee, Wan Kyu Kim, Sanghyuk Lee |
BMC Bioinformatics |
20110215 |
| Drug Screening |
Polymer based chemical delivery to multichannel capillary patterned cells. |
11(4) |
605-608 |
Sung Hoon Lee, Austen James Heinz, Sung-Eun Choi, Wook Park, Sunghoon Kwon |
Lab on a Chip |
20110211 |
