| Integration Core |
AIMP3/p18 controls translational initiation by mediating the delivery of charged initiator tRNA to initiation complex. |
423(4) |
475-481 |
Taehee Kang, Nam Hoon Kwon, Jin Young Lee, Min Chul Park, Eunji Kang, Hyo Hyun Kim, Taek Jin Kang, Sunghoon Kim |
Journal of Molecular Biology |
20121102 |
| Integration Core |
Cancer association study of aminoacyl-tRNA synthetase signaling network in glioblastoma. |
7(8) |
e40960 |
Yong-Wan Kim, ChangHyuk Kwon, Juinn-Lin Liu, Se Hoon Kim, Sunghoon Kim |
PLos One |
20120831 |
| Integration Core |
CDA: Combinatorial drug discovery using transcriptional response modules. |
7(8) |
1-10 |
Ji-Hyun Lee, Dae Gyu Kim, Tae Jeong Bae, Kyoohyoung Rho, Ji-Tae Kim, Jong-Jun Lee, Yeongjun Jang, Byung Cheol Kim, Kyoung Mii Park, Sunghoon Kim |
PLoS One |
20120808 |
| Target ID |
The diagnostic utility of the GNAS mutation in patients with fibrous dysplasia: meta-analysis of 168 sporadic cases. |
43(8) |
1234-1242 |
Seung Eun Lee, Eun Hee Lee, Heejung Park, Ji-Youn Sung, Hyoun Wook Lee, So Young Kang, Sungwook Seo, Byung Heon Kim, Hyojin Lee, An Na Seo, Geunghwan Ahn, Yoon-La Choi |
Human Pathology |
20120801 |
| Drug Screening |
Srs2 possesses a non-canonical PIP box in front of its SBM for precise recognition of SUMOylated PCNA. |
4(4) |
258-261 |
Seong Ok Kim, Hyerim Yoon, Seong Oak Park, Miju Lee, Jae-Sun Shin, Kyoung-Seok Ryu, Jie-Oh Lee, Yeon-soo Seo, Hyun Suk Jung, Byong-Seok Choi |
Journal of Molecular Cell Biology |
20120709 |
| Integration Core |
Identification of CD23 as a functional receptor for the proinflammatory cytokine AIMP1/p43. |
125 |
4620–4629 |
Hyuk-Sang Kwon, Min Chul Park, Dae Gyu Kim, Ki Won Jo, Young Woo Park, Jung Min Han, Sunghoon Kim |
Journal of Cell Science |
20120705 |
| Integration Core |
Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug. |
6(1) |
e80 |
Hee Sook Lee, Taejeong Bae, Ji-Hyun Lee, Dae Gyu Kim, Young Sun Oh, Yeongjun Jang, Ji-Tea Kim, Jong-Jun Lee, Alessio Innocenti, Claudiu T Supuran, Luonan Chen, Kyoohyoung Rho, Sunghoon Kim |
BMC Systems Biology |
20120702 |
| Integration Core |
Interaction of two translational components, lysyl-tRNA synthetase and p40/37LRP, in plasma membrane promotes laminin-dependent cell migration. |
26(10) |
4142-4159 |
Dae Gyu Kim, Jin Woo Choi, Jin Young Lee, Hyerim Kim, Young Sun Oh, Jung Weon Lee, Yu Kyung Tak, Joon Myong Song, Razin Ehud, Seok-Hyun Yun, Sunghoon Kim |
The FASEB Journal |
20120702 |
| Target ID |
Expression profiling of more than 3500 proteins of MSS-type colorectal cancer by stable isotope labeling and mass spectrometry. |
75(10) |
3050-3062 |
Un-Beam Kang, Jeonghun Yeom, Hye-Jung Kim, Hoguen Kim, Cheolju Lee |
Journal of Proteomics |
20120606 |
| Integration Core |
Splicing variant of AIMP2 as an effective target against chemoresistant ovarian cancer. |
4(3) |
164-173 |
Jin Woo Choi, Jeong-Won Lee, Jun Ki Kim, Hye-Kyung Jeon, Jung-Joo Choi, Dae Gyu Kim, young-Gie Kim, Do-Hyun Nam, Hong Joong Kim, Seok Hyun Yun, Sunghoon Kim |
Journal of Molecular Cell Biology |
20120604 |
| Integration Core |
AIMP1 deficiency enhances airway hyperreactivity in mice via increased TH2 immune responses. |
143(3) |
256–265 |
Hye-Jin Hong, Eugene Kim, Mi Young Jung, Sunghoon Kim, Tae Sung Kim |
Clinical Immunology |
20120601 |
| Target ID |
Discovery of ALK-PTPN3 gene fusion from human non-small cell lung carcinoma cell line using next generation RNA sequencing. |
51(6) |
590-597 |
Yeonjoo Jung, Pora Kim, Yeonhwa Jung, Juhee Keum, Soon-Nam Kim, Yong Soo Choi, In-Gu Do, Jinseon Lee, So-Jung Choi, Sujin Kim, Jong-Eun Lee, Jhingook Kim, Sanghyuk Lee, Jaesang Kim |
Genes Chromosomes Cancer |
20120601 |
| Target ID |
Mutated IDH1 is a favorable prognostic factor for type 2 gliomatosis cerebri. |
22(3) |
307-317 |
Mi Jung Kwon, Sung Tae Kim, Mi Jeong Kwon, Doo-Sik Kong, Dageun Lee, Sanghui Park, So Young Kang, Ji-Young Song, Do-Hyun Nam, Yukinari Kato, Yoon-La Choi, Yeon-Lim Suh |
Brain Pathology |
20120501 |
| Disease Modeling |
Oxidative stress-induced biomarkers for stem cell-based chemical screening. |
54 Suppl |
S42-49 |
Se-Ran Yanga, Irfan Rahmand, James E. Troskoe, Kyung-Sun Kang |
Preventive Medicine |
20120501 |
| Integration Core |
Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling. |
8(6) |
547-554 |
Mathew Sajish, Quansheng Zhou, Shuji Kishi, Delgado M Valdez Jr, Mili Kapoor, Min Guo, Sunhee Lee, Sunghoon Kim, Xiang-Lei Yang, Paul Schimmel |
Nature Chemical Biology |
20120415 |
| Integration Core |
Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway. |
149(2) |
410-424 |
Jung Min Han, Seung Jae Jeong, Min Chul Park, Gyuyoup Kim, Nam Hoon Kwon, Hoi Kyoung Kim, Sang Hoon Ha, Sung Ho Ryu, Sunghoon Kim |
Cell |
20120413 |
| Drug Screening |
Asymmetric mode of Ca²⁺-S100A4 interaction with nonmuscle myosin IIA generates nanomolar affinity required for filament remodeling. |
20(4) |
654-666 |
Paul R. Elliott, Andrew F. Irvine, Hyun Suk Jung, Kaeko Tozawa, Martyna W. Pastok, Remigio Picone, Sandip K. Badyal, Jaswir Basran, Philip S. Rudland, Roger Barraclough, Lu-Yun Lian, Clive R. Bagshaw, Marina Kriajevska, Igor L. Barsukov |
Structure |
20120404 |
| Target ID |
A prognostic model for lymph node-negative breast cancer patients based on the integration of proliferation and immunity. |
132(2) |
499-509 |
Ensel Oh, Yoon-La Choi, Taesung Park, Seungyeoun Lee, Seok Jin Nam, Young Kee Shin |
Breast Cancer Research and Treatment |
20120401 |
| Integration Core |
Chemical modulators working at pharmacological interface of target proteins. |
20(6) |
1893-1901 |
Young Ho Jeon, Jin Young Lee, Sunghoon Kim |
Bioorganic & Medicinal Chemistry |
20120315 |
| Target ID |
Chemical modulators working at pharmacological interface of target proteins. |
20(6) |
1893-1901 |
Young Ho Jeon, Jin Young Lee, Sunghoon Kim |
Bioorganic & Medicinal Chemistry |
20120315 |
| Integration Core |
Secreted human glycyl-tRNA synthetase implicated in defense against ERK-activated tumorigenesis. |
109(11) |
E640-647 |
Min Chul Park, Taehee Kang, Da Jin, Jung Min Han, Sang Bum Kim, Yoon Chung Park, Kiwon Cho, Young Woo Park, Weiwei He, Xiang-Lei Yang, Paul Schimmel, Sunghoon Kim |
Proceedings of the National Academy of Sciences of the United States of America |
20120313 |
| Target ID |
Crystal structure of the NurA-dAMP-Mn2+ complex. |
40(5) |
2258-2570 |
Jina Chae, Young Chang Kim, Yunje Cho |
Nucleic Acids Research |
20120301 |
| Target ID |
Clinical significance of CD151 overexpression in subtypes of invasive breast cancer. |
106(5) |
923-930 |
Kwon MJ, Park S, Choi JY, Oh E, Kim YJ, Park YH, Cho EY, Kwon MJ, Nam SJ, Im YH, Shin YK, Choi YL |
British Journal of Cancer |
20120228 |
| Disease Modeling |
Gefitinib resistance of cancer cells correlated with TM4SF5-mediated epithelial-mesenchymal transition. |
1823(2) |
514-523 |
Mi-Sook Lee, Hwang-Phill Kim, Tae-You Kim, Jung Weon Lee |
Biochimica et Biophysica Acta |
20120201 |
| Disease Modeling |
Antagonistic regulation of transmembrane 4 L6 family member 5 attenuates fibrotic phenotypes in CCl(4) -treated mice. |
279(4) |
625-35 |
Minkyung Kang, Soo-Jin Jeong, Sook Young Park, Hyo Jeong Lee, Hyun Jeong Kim, Ki Hun Park, Sang-Kyu Ye, Sung-Hoon Kim, Jung Weon Lee |
FEBS Journal |
20120201 |
| Disease Modeling |
JNK signaling activity regulates cell-cell adhesions via TM4SF5-mediated p27(Kip1) phosphorylation. |
314(2) |
198-205 |
Hyeonjung Kim, Oisun Jung, Minkyung Kang, Mi-Sook Lee, Doyoung Jeong, Jihye Ryu, Youra Ko, Yoon-Ju Choi, Jung Weon Lee |
Cancer Letters |
20120128 |
| Target ID |
Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane. |
26(1) |
219-228 |
Jeong Soon Par, Woo Cheol Lee, Kwon Joo Yeo, Kyoung-Seok Ryu, Malika Kumarasiri, Dusan Hesek, Mijoon Lee, Shahriar Mobashery, Jung Hyun Song, Seung Il Kim, Je Chul Lee, Chaejoon Cheong, Young Ho Jeon, Hye-Yeon Kim |
FASEB Journal |
20120101 |
